SRSF9

Across TCGA patient cohorts, SRSF9 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. CESC shows the largest number of these associations.

The most reproducible SRSF9-associated genes across cancer lineages are RNU2-47P, COPRSP1, and RNU4ATAC11P. Each is linked with SRSF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRSF9-to-partner and partner-to-SRSF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-47P grouped by SRSF9-low versus SRSF9-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF9→partner) and Y-score (partner→SRSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU2-47P →	+0.628	+8.055	<.001	.007	3	2
CESC	COPRSP1 →	+0.085	+4.653	<.001	.004	3	1
CESC	RNU4ATAC11P →	+0.292	+4.705	.003	.003	3	1
CESC	RNU6-1110P →	+0.881	+4.760	<.001	.003	3	1
CESC	LINC01414 →	+0.164	+4.320	.003	.007	3	1
CESC	OR7E10P →	+0.040	+5.144	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

RNU2-47P by SRSF9 expression — BRCA

Explore this box plot interactively →