SRSF9

Across TCGA cell cohorts, SRSF9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,692 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SRSF9-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Regulation of DNA-templated DNA replication initiation, and mRNA alternative polyadenylation. Each is linked with SRSF9 in more than 13 cancer types. Because this analysis shows association rather than direction, both SRSF9-to-partner and partner-to-SRSF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by SRSF9-low versus SRSF9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF9→partner) and Y-score (partner→SRSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA strand elongation involved in DNA replication →	+0.184	+0.598	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated DNA replication initiation →	+0.130	+0.805	<.001	<.001	3	14
BONE	mRNA alternative polyadenylation →	+0.120	+0.758	<.001	<.001	3	14
BONE	Leading strand elongation →	+0.143	+0.535	<.001	<.001	3	13
BONE	Double-strand break repair via break-induced replication →	+0.232	+0.742	.009	<.001	3	13
PANCREAS	Translation reinitiation →	+0.083	+0.637	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,692 associations by consensus.

DNA strand elongation involved in DNA replication by SRSF9 expression — BONE

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