SRSF8

Across TCGA cell cohorts, SRSF8 protein abundance is significantly associated with the RNA expression of many other genes, with 4,385 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SRSF8-associated genes across cancer lineages are HNRNPC, RBMX, and CHTOP. Each is linked with SRSF8 in more than 8 cancer types. Because this analysis shows association rather than direction, both SRSF8-to-partner and partner-to-SRSF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF8 versus HNRNPC in LIVER, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF8→partner) and Y-score (partner→SRSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	HNRNPC →	+0.586	+0.711	.001	.008	3	9
BLOOD_Leukemia	RBMX →	+0.631	+0.351	<.001	<.001	3	8
BREAST	CHTOP →	+0.555	+0.812	<.001	<.001	3	8
BREAST	LRRC40 →	+0.605	+0.617	<.001	<.001	3	8
KIDNEY	NASP →	+0.674	+0.718	.005	.003	3	8
LUNG_SCLC	SRSF7 →	+0.506	+0.693	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,385 associations by consensus.

SRSF8 vs HNRNPC — LIVER

Explore this scatter interactively →