SRSF5

Across TCGA patient cohorts, SRSF5 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,722 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SRSF5-associated proteins across cancer lineages are FNDC3B, FNDC3B_S208, and DCAF5. Each is linked with SRSF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both SRSF5-to-partner and partner-to-SRSF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF5 versus FNDC3B in BRCA, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF5→partner) and Y-score (partner→SRSF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FNDC3B →	-0.550	-0.718	<.001	<.001	3	7
UCEC	FNDC3B_S208 →	-0.618	-0.745	<.001	<.001	3	7
HNSC	DCAF5 →	+0.388	+0.761	<.001	<.001	3	6
BRCA	HSP90B1 →	-0.408	-0.711	<.001	<.001	3	6
HNSC	UBR7 →	+0.326	+0.766	<.001	.009	3	6
GBM	YLPM1 →	+0.232	+0.249	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,722 associations by consensus.

SRSF5 vs FNDC3B — BRCA

Explore this scatter interactively →