SRSF3

Across TCGA patient cohorts, SRSF3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,569 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRSF3-associated genes across cancer lineages are JPH2, DDX55, and TRMT13. Each is linked with SRSF3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SRSF3-to-partner and partner-to-SRSF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF3 versus JPH2 in HNSC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF3→partner) and Y-score (partner→SRSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	JPH2 →	-0.861	-0.173	.001	.002	3	7
UCEC	DDX55 →	+0.565	+0.165	<.001	.002	3	6
HNSC	TRMT13 →	+0.469	+0.147	<.001	<.001	3	6
HNSC	TIMM8A →	+0.701	+0.222	<.001	<.001	3	6
UCEC	ZNF740 →	+0.651	+0.177	<.001	<.001	3	6
UCEC	USP21 →	+0.560	+0.167	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,569 associations by consensus.

SRSF3 vs JPH2 — HNSC

Explore this scatter interactively →