SRSF3

Across TCGA cell cohorts, SRSF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,914 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SRSF3-associated GO terms across cancer lineages are Chromosome condensation, DNA replication, and DNA strand elongation involved in DNA replication. Each is linked with SRSF3 in more than 18 cancer types. Because this analysis shows association rather than direction, both SRSF3-to-partner and partner-to-SRSF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosome condensation grouped by SRSF3-low versus SRSF3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF3→partner) and Y-score (partner→SRSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chromosome condensation →	+0.175	+0.793	<.001	<.001	3	19
BONE	DNA replication →	+0.095	+0.522	<.001	.004	3	19
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation involved in DNA replication →	+0.189	+1.220	<.001	<.001	3	19
PANCREAS	Regulation of DNA replication →	+0.106	+1.113	<.001	<.001	3	19
URINARY_TRACT	Regulation of DNA-templated DNA replication →	+0.112	+0.826	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.256	+1.178	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,914 associations by consensus.

Chromosome condensation by SRSF3 expression — BONE

Explore this box plot interactively →