SRSF10P1

Across TCGA pan-cancer cohorts, SRSF10P1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated SRSF10P1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher SRSF10P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SRSF10P1 expression acts as an unfavorable survival marker, although some lineages such as LAML and ESCA show a favorable association.

READ, THCA, and MESO are the cancer types where SRSF10P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	II,III,IV	0.272	0.810	.002	51	view →
THCA	DFS	Quartile	II,III,IV	0.538	0.825	<.001	46	view →
MESO	OS	Quartile	All	0.204	0.621	.008	34	view →
HNSC	DFS	Tertile	II,III,IV	0.383	0.611	.004	31	view →
CESC	OS	Quartile	All	0.772	0.899	.003	30	view →
LAML	DFS	Median	All	0.481	0.218	.002	30	view →
UCEC	DFS	Tertile	All	0.785	0.862	.007	28	view →
UCS	DFS	Median	II,III,IV	0.191	0.495	.006	26	view →
LIHC	OS	Tertile	All	0.405	0.604	.006	18	view →
KIRC	OS	Median	All	0.549	0.689	.007	15	view →
LGG	DFS	Quartile	All	0.714	0.849	.006	11	view →
COAD	DFS	Tertile	III,IV	0.540	0.696	.028	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

SRSF10P1–READ (OS)

Open the READ breakdown →