Across TCGA patient cohorts, SRSF10 protein abundance is significantly associated with the RNA expression of many other genes, with 14,568 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRSF10-associated genes across cancer lineages are VSIG4, C1S, and LUC7L3. Each is linked with SRSF10 in more than 5 cancer types. Because this analysis shows association rather than direction, both SRSF10-to-partner and partner-to-SRSF10 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF10→partner) and Y-score (partner→SRSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VSIG4 →	-1.250	-0.274	<.001	<.001	3	6
GBM	C1S →	-1.464	-0.288	<.001	<.001	3	6
LSCC	LUC7L3 →	+0.633	+0.212	<.001	<.001	3	6
HNSC	MBTD1 →	+0.507	+0.167	<.001	<.001	3	6
HNSC	RBMX →	+0.855	+0.170	.008	.004	3	6
UCEC	GAS5 →	+0.754	+0.187	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,568 associations by consensus.

Exploration

SRSF10 survival (RNA) · tumor vs normal (RNA) · all SRSF10 data types