Across TCGA patient cohorts, SRSF10 mutation is significantly associated with the RNA expression of many other genes, with 3,229 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SRSF10-associated genes across cancer lineages are RNA5SP411, RNU6-1318P, and RNU6-218P. Each is linked with SRSF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRSF10-to-partner and partner-to-SRSF10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF10→partner) and Y-score (partner→SRSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.278	+2.563	<.001	<.001	3	2
SKCM	RNU6-1318P →	+0.481	+5.292	<.001	.006	3	2
UCEC	RNU6-218P →	+0.478	+2.056	.001	.003	3	2
SKCM	SNORD114-14 →	+0.812	+6.797	<.001	<.001	3	2
HNSC	CENPVL1 →	+0.019	+7.954	<.001	.008	3	1
UCEC	YTHDF3-AS1 →	+0.552	+3.346	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,229 associations by consensus.

Exploration

SRSF10 survival (RNA) · tumor vs normal (RNA) · all SRSF10 data types