Across TCGA cell cohorts, SRRM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,866 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SRRM5-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, mRNA splice site recognition, and Spliceosomal complex assembly. Each is linked with SRRM5 in more than 17 cancer types. Because this analysis shows association rather than direction, both SRRM5-to-partner and partner-to-SRRM5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRRM5→partner) and Y-score (partner→SRRM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.183	+0.506	<.001	<.001	3	18
URINARY_TRACT	mRNA splice site recognition →	+0.150	+0.776	<.001	<.001	3	17
OESOPHAGUS	Spliceosomal complex assembly →	+0.093	+0.745	.004	<.001	3	17
LARGE_INTESTINE	Regulation of RNA splicing →	+0.080	+0.565	<.001	<.001	3	16
OESOPHAGUS	Negative regulation of DNA-templated transcription, elongation →	+0.111	+0.557	.001	<.001	3	16
BONE	Negative regulation of gene expression, epigenetic →	+0.101	+0.627	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,866 associations by consensus.

Exploration

SRRM5 survival (RNA) · tumor vs normal (RNA) · all SRRM5 data types