SRRM4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SRRM4 protein abundance is significantly associated with the RNA expression of many other genes, with 891 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRRM4-associated genes across cancer lineages are RNU6-813P, PRELID2P1, and ACR. Each is linked with SRRM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRRM4-to-partner and partner-to-SRRM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRRM4 versus RNU6-813P in GBM, with a Pearson correlation of 0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRRM4→partner) and Y-score (partner→SRRM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRNU6-813P →+1.460+0.649.002<.00132
LUADPRELID2P1 →+2.211+2.956.007<.00132
LUADACR →+0.125+2.955.001<.00131
LUADCACNA1F →+1.476+4.076.003<.00131
LUADLUZP4 →+0.166+2.955.001<.00131
LUADPORCN →+0.614+2.955.008<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 891 associations by consensus.

SRRM4 vs RNU6-813P — GBM

Per-sample scatter of SRRM4 vs RNU6-813P in GBM (Pearson r = 0.90).

Explore this scatter interactively →

Exploration