SRRM4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SRRM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,182 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SRRM4-associated GO terms across cancer lineages are Regulation of systemic arterial blood pressure, Regulation of chemotaxis, and Regulation of hemostasis. Each is linked with SRRM4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SRRM4-to-partner and partner-to-SRRM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of systemic arterial blood pressure grouped by SRRM4-low versus SRRM4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRRM4→partner) and Y-score (partner→SRRM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONERegulation of systemic arterial blood pressure →-0.149-1.723<.001<.00136
BONERegulation of chemotaxis →-0.098-2.037.001.00736
BONERegulation of hemostasis →-0.184-1.591<.001<.00135
BONERegulation of protein maturation →-0.191-1.707<.001<.00135
BONERegulation of blood coagulation →-0.181-1.591<.001<.00135
LUNG_SCLCRegulation of T-helper 1 cell differentiation →-1.004-1.251<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,182 associations by consensus.

Regulation of systemic arterial blood pressure by SRRM4 expression — BONE

Box plot of Regulation of systemic arterial blood pressure in SRRM4-low vs SRRM4-high samples in BONE.

Explore this box plot interactively →

Exploration