SRRM1

Across TCGA patient cohorts, SRRM1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,444 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRRM1-associated genes across cancer lineages are CENPM, FOXM1, and RFC5. Each is linked with SRRM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SRRM1-to-partner and partner-to-SRRM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRRM1 versus CENPM in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRRM1→partner) and Y-score (partner→SRRM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CENPM →	+1.057	+0.153	<.001	.001	3	5
BRCA	FOXM1 →	+1.186	+0.218	<.001	.001	3	5
LSCC	RFC5 →	+0.779	+0.239	<.001	<.001	3	5
BRCA	CDCA3 →	+0.731	+0.159	<.001	<.001	3	5
BRCA	FANCE →	+0.724	+0.178	.002	.007	3	5
UCEC	HJURP →	+0.950	+0.223	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,444 associations by consensus.

SRRM1 vs CENPM — HNSC

Explore this scatter interactively →