SRPX2

Across TCGA patient cohorts, SRPX2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,255 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRPX2-associated genes across cancer lineages are COL1A1, SPARC, and ITGA11. Each is linked with SRPX2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SRPX2-to-partner and partner-to-SRPX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRPX2 versus COL1A1 in COAD, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPX2→partner) and Y-score (partner→SRPX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	COL1A1 →	+2.008	+0.614	<.001	.003	3	10
HNSC	SPARC →	+1.417	+0.883	<.001	<.001	3	10
OV	ITGA11 →	+1.804	+0.745	<.001	.001	3	10
GBM	COL6A3 →	+1.772	+0.719	<.001	<.001	3	10
OV	MSRB3 →	+1.480	+0.834	<.001	<.001	3	10
COAD	CALHM5 →	+0.937	+0.849	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,255 associations by consensus.

SRPX2 vs COL1A1 — COAD

Explore this scatter interactively →