SRPX2

Across TCGA cell cohorts, SRPX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,765 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SRPX2-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Protein activation cascade, and Gastrulation. Each is linked with SRPX2 in more than 13 cancer types. Because this analysis shows association rather than direction, both SRPX2-to-partner and partner-to-SRPX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by SRPX2-low versus SRPX2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPX2→partner) and Y-score (partner→SRPX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Small GTPase-mediated signal transduction →	+0.072	+3.123	<.001	<.001	3	14
OESOPHAGUS	Protein activation cascade →	+0.365	+3.000	<.001	<.001	3	14
SOFT_TISSUE	Gastrulation →	+0.114	+2.711	<.001	<.001	3	13
BONE	Viral process →	+0.113	+3.479	<.001	<.001	3	13
BONE	Regulation of response to wounding →	+0.161	+2.910	<.001	<.001	3	13
STOMACH	Regulation of proteolysis →	+0.143	+2.079	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,765 associations by consensus.

Small GTPase-mediated signal transduction by SRPX2 expression — BONE

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