SRPK2

Across TCGA patient cohorts, SRPK2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,263 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRPK2-associated genes across cancer lineages are BUD31, DNAJC2, and CHCHD3. Each is linked with SRPK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SRPK2-to-partner and partner-to-SRPK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRPK2 versus BUD31 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPK2→partner) and Y-score (partner→SRPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BUD31 →	+0.758	+0.493	<.001	<.001	3	7
LSCC	DNAJC2 →	+0.526	+0.304	<.001	<.001	3	6
UCEC	CHCHD3 →	+0.598	+0.322	.009	.001	3	6
LSCC	ORC5 →	+0.582	+0.290	<.001	<.001	3	6
GBM	ZNF92 →	+0.841	+0.407	<.001	<.001	3	6
HNSC	PSMC2 →	+0.572	+0.430	.005	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,263 associations by consensus.

SRPK2 vs BUD31 — HNSC

Explore this scatter interactively →