SRPK2

Across TCGA cell cohorts, SRPK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,814 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SRPK2-associated GO terms across cancer lineages are Peptidyl-serine phosphorylation, Peptidyl-serine modification, and Golgi vesicle transport. Each is linked with SRPK2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SRPK2-to-partner and partner-to-SRPK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-serine phosphorylation grouped by SRPK2-low versus SRPK2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPK2→partner) and Y-score (partner→SRPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Peptidyl-serine phosphorylation →	+0.068	+0.768	<.001	<.001	3	13
SKIN	Peptidyl-serine modification →	+0.068	+0.706	<.001	<.001	3	13
BONE	Golgi vesicle transport →	+0.065	+0.721	.005	.004	3	13
BLOOD_Lymphoma	Establishment of protein localization to organelle →	+0.046	+1.143	<.001	<.001	3	13
OESOPHAGUS	Regulation of hematopoietic stem cell differentiation →	+0.128	+0.811	<.001	<.001	3	12
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.112	+1.306	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,814 associations by consensus.

Peptidyl-serine phosphorylation by SRPK2 expression — SKIN

Explore this box plot interactively →