SRP9

Across TCGA pan-cancer cohorts, SRP9 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SRP9 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SRP9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SRP9 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, HNSC, and CCRCC are the cancer types where SRP9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	1.000	0.892	.001	35	view →
HNSC	DFS	Median	III,IV	0.903	1.000	.004	24	view →
CCRCC	DFS	Tertile	All	0.732	0.928	.008	19	view →
LUAD	DFS	Median	III,IV	0.315	0.948	.008	8	view →
PDAC	DFS	Median	All	0.459	0.251	.005	7	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SRP9–LSCC (DFS)

Open the LSCC breakdown →