SRP68

Across TCGA cell cohorts, SRP68 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SRP68-associated genes across cancer lineages are ZNF804B and EPPIN. Each is linked with SRP68 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRP68-to-partner and partner-to-SRP68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF804B grouped by SRP68-low versus SRP68-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRP68→partner) and Y-score (partner→SRP68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	ZNF804B →	+0.006	+5.087	<.001	.004	3	1
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ZNF804B by SRP68 expression — URINARY_TRACT

Explore this box plot interactively →