SRP54

Across TCGA patient cohorts, SRP54 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,127 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SRP54-associated proteins across cancer lineages are FKBP3, HEATR5A, and ARHGAP5. Each is linked with SRP54 in more than 7 cancer types. Because this analysis shows association rather than direction, both SRP54-to-partner and partner-to-SRP54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRP54 versus FKBP3 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRP54→partner) and Y-score (partner→SRP54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FKBP3 →	+0.352	+0.513	<.001	<.001	3	8
OV	HEATR5A →	+0.325	+0.558	<.001	<.001	3	7
HNSC	ARHGAP5 →	+0.429	+0.463	<.001	<.001	3	7
LUAD	GNPNAT1 →	+0.443	+0.395	<.001	<.001	3	6
COAD	HSP90AA1 →	+0.342	+0.502	<.001	<.001	3	6
GBM	SSRP1 →	+0.399	+0.342	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,127 associations by consensus.

SRP54 vs FKBP3 — HNSC

Explore this scatter interactively →