SRP14

Across TCGA patient cohorts, SRP14 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SRP14-associated genes across cancer lineages are Th2 cells and pDC. Each is linked with SRP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRP14-to-partner and partner-to-SRP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by SRP14-low versus SRP14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRP14→partner) and Y-score (partner→SRP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Th2 cells →	+0.245	+3.000	.019	.037	3	1
UCEC	pDC →	+0.059	+3.010	.035	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Th2 cells by SRP14 expression — UCEC

Explore this box plot interactively →