SRM

Across TCGA cell cohorts, SRM RNA expression is significantly associated with the RNA expression of many other genes, with 9,512 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SRM-associated genes across cancer lineages are DFFA, MRTO4, and ATAD3A. Each is linked with SRM in more than 18 cancer types. Because this analysis shows association rather than direction, both SRM-to-partner and partner-to-SRM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRM versus DFFA in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.75.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRM→partner) and Y-score (partner→SRM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DFFA →	+1.103	+1.176	.003	.005	3	19
BLOOD_Myeloma	MRTO4 →	+1.264	+1.296	<.001	<.001	3	19
SKIN	ATAD3A →	+1.367	+1.061	<.001	<.001	3	18
KIDNEY	TMEM201 →	+1.391	+1.482	<.001	<.001	3	17
LUNG_NSCLC_LUSC	NOC2L →	+1.137	+1.587	.002	<.001	3	17
PANCREAS	RRP9 →	+1.173	+1.307	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,512 associations by consensus.

SRM vs DFFA — LUNG_NSCLC_LUSC

Explore this scatter interactively →