Across TCGA patient cohorts, SRL RNA expression is significantly associated with the protein abundance of many other proteins, with 18,394 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SRL-associated proteins across cancer lineages are ITGA7, LMOD1, and CAVIN2. Each is linked with SRL in more than 6 cancer types. Because this analysis shows association rather than direction, both SRL-to-partner and partner-to-SRL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRL→partner) and Y-score (partner→SRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ITGA7 →	+1.138	+0.289	<.001	<.001	3	7
UCEC	LMOD1 →	+1.048	+0.398	<.001	.001	3	7
BRCA	CAVIN2 →	+0.733	+0.173	<.001	<.001	3	7
CCRCC	CD34 →	+0.781	+0.456	<.001	<.001	3	7
UCEC	FHL5 →	+1.096	+0.568	<.001	<.001	3	7
BRCA	NOSTRIN →	+0.743	+0.179	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,394 associations by consensus.

Exploration

SRL survival (RNA) · tumor vs normal (RNA) · all SRL data types