Across TCGA cell cohorts, SRL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,231 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SRL-associated GO terms across cancer lineages are Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, Phospholipid biosynthetic process, and Cytoplasmic translation. Each is linked with SRL in more than 6 cancer types. Because this analysis shows association rather than direction, both SRL-to-partner and partner-to-SRL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRL→partner) and Y-score (partner→SRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.123	+0.087	<.001	.003	3	6
BREAST	Phospholipid biosynthetic process →	+0.044	+0.065	<.001	<.001	3	6
BREAST	Cytoplasmic translation →	+0.065	+0.051	.001	.006	3	6
STOMACH	Glycerolipid biosynthetic process →	+0.042	+0.115	<.001	.001	2	7
PANCREAS	Viral process →	+0.061	+0.073	.002	<.001	3	5
PANCREAS	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.061	+0.058	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,231 associations by consensus.

Exploration

SRL survival (RNA) · tumor vs normal (RNA) · all SRL data types