Across TCGA pan-cancer cohorts, SRIP3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SRIP3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SRIP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SRIP3 is over-expressed in tumor.

COAD and HNSC are the cancer types where SRIP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SRIP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.141	<.001	4	view →
HNSC	All	II,III,IV	+0.059	.026	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SRIP3 RNA expression & survival · all SRIP3 data types