Across TCGA pan-cancer cohorts, SRIP2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SRIP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SRIP2 RNA is repressed in tumor relative to normal tissue. In most cancer types SRIP2 is over-expressed in tumor, although a few such as COAD and LUAD show the opposite, repressed pattern.

COAD and LUAD are the cancer types where SRIP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SRIP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.094	.039	2	view →
LUAD	All	All	−0.051	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SRIP2 RNA expression & survival · all SRIP2 data types