SRIP1

Across TCGA pan-cancer cohorts, SRIP1 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated SRIP1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SRIP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SRIP1 expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

UCEC, THYM, and HNSC are the cancer types where SRIP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.447	0.690	<.001	66	view →
THYM	OS	Tertile	All	0.736	0.974	.006	63	view →
HNSC	DFS	Tertile	II,III,IV	0.202	0.666	.004	36	view →
ACC	OS	Tertile	III,IV	0.189	0.757	<.001	18	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	9	view →
LUSC	OS	Tertile	All	0.797	0.452	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SRIP1–UCEC (OS)

Open the UCEC breakdown →