SRI

Across TCGA patient cohorts, SRI RNA expression is significantly associated with the protein abundance of many other proteins, with 8,842 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SRI-associated proteins across cancer lineages are CKAP4_S26, PPP1R9A, and ARMC10. Each is linked with SRI in more than 4 cancer types. Because this analysis shows association rather than direction, both SRI-to-partner and partner-to-SRI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRI versus CKAP4_S26 in BRCA, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRI→partner) and Y-score (partner→SRI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CKAP4_S26 →	-0.604	-0.308	<.001	.003	3	5
LUAD	PPP1R9A →	+0.465	+0.634	<.001	<.001	3	4
HNSC	ARMC10 →	+0.438	+0.835	<.001	<.001	3	4
GBM	PLEKHO2_T311 →	-0.467	-0.460	<.001	.004	3	4
BRCA	SEC11C →	-0.845	-0.541	<.001	<.001	3	4
BRCA	SRP68 →	-0.286	-0.526	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,842 associations by consensus.

SRI vs CKAP4_S26 — BRCA

Explore this scatter interactively →