Across TCGA patient cohorts, SRGAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,569 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRGAP3-associated genes across cancer lineages are SRGAP3-AS2, ABCC5, and PAK5. Each is linked with SRGAP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SRGAP3-to-partner and partner-to-SRGAP3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRGAP3→partner) and Y-score (partner→SRGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRGAP3-AS2 →	+0.956	+0.449	<.001	<.001	3	5
LSCC	ABCC5 →	+1.410	+0.387	<.001	<.001	3	4
LSCC	PAK5 →	+1.148	+0.392	<.001	<.001	3	4
BRCA	ENTPD3 →	+1.010	+0.392	.002	.001	3	4
LSCC	SRGAP3-AS3 →	+1.078	+0.595	<.001	<.001	3	4
LSCC	ACSS1 →	+0.893	+0.478	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,569 associations by consensus.

Exploration

SRGAP3 survival (RNA) · tumor vs normal (RNA) · all SRGAP3 data types