Across TCGA pan-cancer cohorts, SRGAP3-AS3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SRGAP3-AS3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SRGAP3-AS3 RNA is repressed in tumor relative to normal tissue. In most cancer types SRGAP3-AS3 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC and STAD are the cancer types where SRGAP3-AS3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SRGAP3-AS3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	−0.044	.013	5	view →
STAD	All	III,IV	+0.232	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SRGAP3-AS3 RNA expression & survival · all SRGAP3-AS3 data types