Across TCGA patient cohorts, SRGAP2B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,376 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SRGAP2B-associated proteins across cancer lineages are YARS2, SRGAP2, and CRTAP. Each is linked with SRGAP2B in more than 5 cancer types. Because this analysis shows association rather than direction, both SRGAP2B-to-partner and partner-to-SRGAP2B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRGAP2B→partner) and Y-score (partner→SRGAP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YARS2 →	-0.661	-0.749	<.001	<.001	3	6
GBM	SRGAP2 →	+0.308	+0.409	<.001	<.001	3	5
BRCA	CRTAP →	+0.416	+0.267	.003	.005	3	5
COAD	GTPBP10 →	-0.460	-0.318	<.001	<.001	3	5
OV	ITGB5 →	+0.563	+0.443	.001	.002	3	5
COAD	PPIF →	-0.425	-0.355	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,376 associations by consensus.

Exploration

SRGAP2B survival (RNA) · tumor vs normal (RNA) · all SRGAP2B data types