Across TCGA cell cohorts, SRGAP2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,614 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SRGAP2B-associated GO terms across cancer lineages are Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration, Centrosome cycle, and Chromosome condensation. Each is linked with SRGAP2B in more than 16 cancer types. Because this analysis shows association rather than direction, both SRGAP2B-to-partner and partner-to-SRGAP2B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRGAP2B→partner) and Y-score (partner→SRGAP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.163	+1.226	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Centrosome cycle →	+0.087	+1.471	.002	.002	3	14
BREAST	Chromosome condensation →	+0.145	+1.607	<.001	<.001	3	14
BONE	Regulation of hippo signaling →	+0.113	+1.461	<.001	<.001	2	15
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.078	+1.573	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.083	+1.186	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,614 associations by consensus.

Exploration

SRGAP2B survival (RNA) · tumor vs normal (RNA) · all SRGAP2B data types