SRGAP2

Across TCGA cell cohorts, SRGAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,091 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SRGAP2-associated GO terms across cancer lineages are Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration, Positive regulation of neuron migration, and Regulation of centriole-centriole cohesion. Each is linked with SRGAP2 in more than 19 cancer types. Because this analysis shows association rather than direction, both SRGAP2-to-partner and partner-to-SRGAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration grouped by SRGAP2-low versus SRGAP2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRGAP2→partner) and Y-score (partner→SRGAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.214	+1.572	<.001	<.001	3	20
LUNG_SCLC	Positive regulation of neuron migration →	+0.130	+1.153	<.001	<.001	3	18
OESOPHAGUS	Regulation of centriole-centriole cohesion →	+0.227	+1.306	<.001	<.001	3	18
LARGE_INTESTINE	Positive regulation of mitotic cytokinesis →	+0.159	+1.662	<.001	<.001	3	17
STOMACH	Cell motility involved in cerebral cortex radial glia guided migration →	+0.179	+1.456	<.001	<.001	3	17
OESOPHAGUS	Regulation of G1/S transition of mitotic cell cycle →	+0.078	+1.192	.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,091 associations by consensus.

Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration by SRGAP2 expression — OESOPHAGUS

Explore this box plot interactively →