SRGAP2-AS1

Across TCGA pan-cancer cohorts, SRGAP2-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SRGAP2-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SRGAP2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SRGAP2-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

COAD, PAAD, and TGCT are the cancer types where SRGAP2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.158	0.521	<.001	117	view →
PAAD	OS	Quartile	II,III,IV	0.883	0.476	<.001	48	view →
TGCT	DFS	Tertile	III,IV	0.340	1.000	.002	42	view →
LUAD	OS	Quartile	All	0.794	0.649	.001	40	view →
ACC	OS	Quartile	III,IV	0.294	0.684	.003	37	view →
KICH	OS	Tertile	II,III,IV	0.474	0.872	.006	36	view →
DLBC	OS	Quartile	All	0.701	0.961	.004	34	view →
ESCA	OS	Median	IV	0.143	0.650	.004	24	view →
LGG	DFS	Tertile	All	0.631	0.850	.001	23	view →
STAD	DFS	Quartile	III,IV	0.564	0.218	.025	21	view →
LUSC	OS	Quartile	II,III,IV	0.509	0.663	.012	20	view →
UCS	DFS	Tertile	IV	0.981	0.510	.020	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SRGAP2-AS1–COAD (DFS)

Open the COAD breakdown →