Across TCGA patient cohorts, SRGAP1 mutation is significantly associated with the RNA expression of many other genes, with 3,484 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SRGAP1-associated genes across cancer lineages are UBE2K, SLAMF8, and C1QC. Each is linked with SRGAP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SRGAP1-to-partner and partner-to-SRGAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRGAP1→partner) and Y-score (partner→SRGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBE2K →	+0.278	+1.547	.008	.008	3	4
COAD	SLAMF8 →	+0.910	+3.469	.001	.002	3	3
UCEC	C1QC →	+0.696	+1.652	.003	.005	3	3
COAD	WDR41 →	+0.451	+1.947	<.001	.009	3	3
UCEC	CENPN →	+0.543	+1.975	<.001	<.001	3	3
UCEC	FBXO22 →	+0.378	+1.801	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,484 associations by consensus.

Exploration

SRGAP1 survival (RNA) · tumor vs normal (RNA) · all SRGAP1 data types