SRFBP1

Across TCGA cell cohorts, SRFBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,426 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SRFBP1-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Positive regulation of rRNA processing, and Mitotic recombination. Each is linked with SRFBP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SRFBP1-to-partner and partner-to-SRFBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by SRFBP1-low versus SRFBP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRFBP1→partner) and Y-score (partner→SRFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Maturation of SSU-rRNA →	+0.128	+0.678	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of rRNA processing →	+0.149	+0.723	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitotic recombination →	+0.128	+0.890	<.001	<.001	3	14
PANCREAS	Positive regulation of centrosome duplication →	+0.098	+0.755	<.001	.004	3	13
SOFT_TISSUE	Protein localization to chromosome →	+0.079	+0.672	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.079	+0.911	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,426 associations by consensus.

Maturation of SSU-rRNA by SRFBP1 expression — OESOPHAGUS

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