SRF

Across TCGA patient cohorts, SRF RNA expression is significantly associated with the protein abundance of many other proteins, with 10,017 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRF-associated proteins across cancer lineages are TBCC, KIF13B, and KIF13B_S1381. Each is linked with SRF in more than 4 cancer types. Because this analysis shows association rather than direction, both SRF-to-partner and partner-to-SRF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRF versus TBCC in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRF→partner) and Y-score (partner→SRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TBCC →	+0.363	+0.520	.001	.001	3	5
HNSC	KIF13B →	-0.351	-0.469	<.001	<.001	3	4
LUAD	KIF13B_S1381 →	-0.953	-0.478	<.001	<.001	3	4
BRCA	AP3B1 →	-0.196	-0.444	<.001	.007	3	4
LSCC	RRBP1 →	-0.375	-0.492	<.001	<.001	3	4
LSCC	SEC24A →	-0.273	-0.366	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,017 associations by consensus.

SRF vs TBCC — OV

Explore this scatter interactively →