SREK1IP1P1

Across TCGA pan-cancer cohorts, SREK1IP1P1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SREK1IP1P1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SREK1IP1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SREK1IP1P1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

LUAD, UVM, and UCEC are the cancer types where SREK1IP1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	IV	0.212	0.777	.001	68	view →
UVM	OS	Tertile	III,IV	0.075	0.814	<.001	60	view →
UCEC	DFS	Quartile	II,III,IV	0.839	0.666	.008	50	view →
LIHC	OS	Tertile	All	0.416	0.625	<.001	49	view →
BLCA	DFS	Median	II,III,IV	0.591	0.457	.004	24	view →
ACC	DFS	Tertile	All	0.281	0.644	.009	19	view →
THCA	DFS	Median	IV	0.942	0.678	.015	15	view →
LUSC	OS	Tertile	III,IV	0.344	0.616	.010	14	view →
PCPG	DFS	Median	All	0.939	0.696	.009	13	view →
PRAD	DFS	Tertile	All	0.959	0.923	.020	12	view →
STAD	DFS	Quartile	IV	0.144	0.589	.006	12	view →
SKCM	DFS	Tertile	IV	1.000	0.068	.029	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SREK1IP1P1–LUAD (DFS)

Open the LUAD breakdown →