SREK1

Across TCGA patient cohorts, SREK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,717 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SREK1-associated proteins across cancer lineages are ERBIN, PPWD1, and VEZF1. Each is linked with SREK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SREK1-to-partner and partner-to-SREK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SREK1 versus ERBIN in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SREK1→partner) and Y-score (partner→SREK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ERBIN →	+0.238	+0.566	<.001	.001	3	6
HNSC	PPWD1 →	+0.324	+0.648	<.001	<.001	3	6
GBM	VEZF1 →	+0.378	+0.521	<.001	<.001	3	5
BRCA	MSH3 →	+0.266	+0.761	<.001	<.001	3	5
GBM	CWC27 →	+0.223	+0.364	<.001	<.001	3	5
BRCA	GPALPP1 →	+0.370	+0.670	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,717 associations by consensus.

SREK1 vs ERBIN — BRCA

Explore this scatter interactively →