SRD5A3P1

Across TCGA pan-cancer cohorts, SRD5A3P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SRD5A3P1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SRD5A3P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SRD5A3P1 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.

LUAD, BRCA, and READ are the cancer types where SRD5A3P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SRD5A3P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.032	.004	4	view →
BRCA	All	All	+0.021	.043	2	view →
READ	All	All	−0.155	.018	1	view →
KIRC	All	All	+0.008	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SRD5A3P1–LUAD

Open the LUAD breakdown →