SRD5A2

Across TCGA cell cohorts, SRD5A2 protein abundance is significantly associated with the RNA expression of many other genes, with 999 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SRD5A2-associated genes across cancer lineages are HSPB8, BCAR3, and GPRC5C. Each is linked with SRD5A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SRD5A2-to-partner and partner-to-SRD5A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRD5A2 versus HSPB8 in LUNG_NSCLC_LUAD, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRD5A2→partner) and Y-score (partner→SRD5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	HSPB8 →	+2.013	+1.028	<.001	.002	3	3
BLOOD_Leukemia	BCAR3 →	+1.029	+2.242	.003	.002	3	3
BLOOD_Leukemia	GPRC5C →	+1.736	+1.981	.003	<.001	3	3
LARGE_INTESTINE	CD276 →	+1.466	+1.486	<.001	.004	3	3
LUNG_SCLC	OST4 →	+0.622	+1.133	.002	.004	3	3
CNS	HMGN3 →	-0.861	-1.650	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 999 associations by consensus.

SRD5A2 vs HSPB8 — LUNG_NSCLC_LUAD

Explore this scatter interactively →