SRD5A1P1

Across TCGA pan-cancer cohorts, SRD5A1P1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated SRD5A1P1 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher SRD5A1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SRD5A1P1 expression acts as an unfavorable survival marker.

TGCT, THYM, and MESO are the cancer types where SRD5A1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	DFS	Tertile	II,III,IV	0.339	0.955	<.001	72	view →
THYM	OS	Tertile	All	0.649	0.911	.002	60	view →
MESO	OS	Tertile	All	0.323	0.569	.021	45	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
ACC	OS	Tertile	II,III,IV	0.135	0.658	.010	27	view →
CESC	OS	Tertile	IV	0.237	0.628	.018	18	view →
COAD	OS	Tertile	IV	0.157	0.669	.010	15	view →
KIRC	DFS	Tertile	All	0.482	0.662	.039	12	view →
BLCA	DFS	Tertile	IV	0.147	0.475	.032	9	view →
CHOL	OS	Tertile	All	0.114	0.623	.033	9	view →
LGG	OS	Tertile	All	0.300	0.479	.017	9	view →
LIHC	DFS	Tertile	II,III,IV	0.304	0.446	.043	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

SRD5A1P1–TGCT (DFS)

Open the TGCT breakdown →