SRCIN1

Across TCGA patient cohorts, SRCIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,113 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRCIN1-associated genes across cancer lineages are CACNA1D, HDAC11, and ARNTL2. Each is linked with SRCIN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SRCIN1-to-partner and partner-to-SRCIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRCIN1 versus CACNA1D in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRCIN1→partner) and Y-score (partner→SRCIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CACNA1D →	+1.365	+0.587	<.001	<.001	3	5
BRCA	HDAC11 →	+0.945	+0.583	<.001	.003	3	5
BRCA	ARNTL2 →	-1.498	-0.664	<.001	<.001	3	4
CCRCC	CDS1 →	+1.089	+1.129	.001	<.001	3	4
CCRCC	CHDH →	+1.251	+1.103	.002	.003	3	4
CCRCC	C1orf210 →	+1.874	+1.201	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,113 associations by consensus.

SRCIN1 vs CACNA1D — BRCA

Explore this scatter interactively →