SRCAP

Across TCGA patient cohorts, SRCAP protein abundance is significantly associated with the protein abundance of many other proteins, with 6,386 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRCAP-associated proteins across cancer lineages are PDCD6IP_S13, PTCD3, and TRA2A_T24. Each is linked with SRCAP in more than 2 cancer types. Because this analysis shows association rather than direction, both SRCAP-to-partner and partner-to-SRCAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRCAP versus PDCD6IP_S13 in BRCA, with a Pearson correlation of -0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRCAP→partner) and Y-score (partner→SRCAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDCD6IP_S13 →	-1.311	-0.708	.001	<.001	3	2
BRCA	PTCD3 →	+0.290	+0.579	.001	<.001	3	2
LUAD	TRA2A_T24 →	+1.522	+0.701	<.001	.002	3	2
GBM	VOPP1 →	-2.188	-0.468	.002	.002	3	2
OV	SRSF7 →	+0.485	+0.185	<.001	.005	2	3
LSCC	TCEA1_S100 →	+0.610	+0.338	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,386 associations by consensus.

SRCAP vs PDCD6IP_S13 — BRCA

Explore this scatter interactively →