SRCAP

Across TCGA cell cohorts, SRCAP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,919 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SRCAP-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Regulation of intracellular steroid hormone receptor signaling pathway, and Epigenetic regulation of gene expression. Each is linked with SRCAP in more than 17 cancer types. Because this analysis shows association rather than direction, both SRCAP-to-partner and partner-to-SRCAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T-helper 17 cell lineage commitment grouped by SRCAP-low versus SRCAP-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRCAP→partner) and Y-score (partner→SRCAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of T-helper 17 cell lineage commitment →	+0.302	+1.568	<.001	.004	3	18
OESOPHAGUS	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.096	+1.484	<.001	.004	3	18
BONE	Epigenetic regulation of gene expression →	+0.103	+1.933	<.001	<.001	3	18
STOMACH	Positive regulation of cell fate commitment →	+0.262	+1.334	<.001	.003	3	17
BONE	CAMP/PKA signal transduction →	+0.236	+1.463	<.001	<.001	3	17
BONE	Regulation of chromatin organization →	+0.095	+1.322	.002	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,919 associations by consensus.

Positive regulation of T-helper 17 cell lineage commitment by SRCAP expression — OESOPHAGUS

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