SRC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SRC RNA expression is significantly associated with the protein abundance of many other proteins, with 9,025 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SRC-associated proteins across cancer lineages are SRC_S17, STAU1, and RPRD1B. Each is linked with SRC in more than 4 cancer types. Because this analysis shows association rather than direction, both SRC-to-partner and partner-to-SRC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRC→partner) and Y-score (partner→SRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCSRC_S17 →+0.690+0.581<.001<.00135
COADSTAU1 →+0.331+0.674<.001<.00135
COADRPRD1B →+0.375+0.572<.001<.00134
COADACOT8 →+0.330+0.544.006<.00134
UCECPECAM1 →-0.382-0.417.009.00834
LSCCFAM114A2 →-0.316-0.581<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,025 associations by consensus.

Exploration