Across TCGA patient cohorts, SRC protein abundance is significantly associated with the RNA expression of many other genes, with 12,478 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRC-associated genes across cancer lineages are NORAD, SDC4, and CALHM2. Each is linked with SRC in more than 5 cancer types. Because this analysis shows association rather than direction, both SRC-to-partner and partner-to-SRC results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRC→partner) and Y-score (partner→SRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NORAD →	+0.523	+0.283	.009	.008	3	6
HNSC	SDC4 →	+0.676	+0.187	<.001	.001	3	5
UCEC	CALHM2 →	-0.768	-0.208	<.001	.006	3	5
LSCC	BLCAP →	+0.621	+0.282	<.001	<.001	3	5
BRCA	PEDS1 →	+0.682	+0.462	<.001	<.001	3	5
COAD	SGK2 →	+0.935	+0.222	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,478 associations by consensus.

Exploration

SRC survival (RNA) · tumor vs normal (RNA) · all SRC data types