SRBD1

Across TCGA cell cohorts, SRBD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,860 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SRBD1-associated GO terms across cancer lineages are Spindle elongation, DNA-templated DNA replication, and Replication fork processing. Each is linked with SRBD1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SRBD1-to-partner and partner-to-SRBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by SRBD1-low versus SRBD1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRBD1→partner) and Y-score (partner→SRBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Spindle elongation →	+0.252	+0.935	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.117	+1.178	.002	<.001	3	15
URINARY_TRACT	Replication fork processing →	+0.087	+0.686	.004	.004	3	15
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.079	+1.062	<.001	<.001	3	15
KIDNEY	Regulation of chromosome segregation →	+0.133	+1.043	<.001	<.001	3	14
SOFT_TISSUE	DNA replication →	+0.113	+1.033	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,860 associations by consensus.

Spindle elongation by SRBD1 expression — KIDNEY

Explore this box plot interactively →