SRARP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SRARP RNA expression is significantly associated with the protein abundance of many other proteins, with 11,659 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRARP-associated proteins across cancer lineages are ZFAND5, REPS2, and RHOB. Each is linked with SRARP in more than 2 cancer types. Because this analysis shows association rather than direction, both SRARP-to-partner and partner-to-SRARP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRARP→partner) and Y-score (partner→SRARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAZFAND5 →-0.474-1.694<.001<.00133
BRCAREPS2 →+0.702+2.293<.001<.00133
BRCARHOB →+0.677+1.797<.001<.00133
GBMCABLES1 →+0.511+0.657<.001<.00133
BRCACEP55_S428 →-0.866-1.437<.001<.00133
BRCADDAH1 →+0.572+1.384<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,659 associations by consensus.

Exploration