Across TCGA patient cohorts, SRARP protein abundance is significantly associated with the RNA expression of many other genes, with 1,363 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRARP-associated genes across cancer lineages are SRRD, EIF3L, and HMGXB4. Each is linked with SRARP in more than 1 cancer types. Because this analysis shows association rather than direction, both SRARP-to-partner and partner-to-SRARP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRARP→partner) and Y-score (partner→SRARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SRRD →	+0.484	+0.902	.001	.001	3	1
BRCA	EIF3L →	+1.189	+0.924	<.001	<.001	3	1
BRCA	HMGXB4 →	+0.989	+0.924	.009	<.001	3	1
BRCA	SLC25A17 →	+0.835	+1.020	<.001	<.001	3	1
BRCA	ST13 →	+1.100	+0.924	<.001	<.001	3	1
BRCA	GNPNAT1 →	+2.428	+1.173	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,363 associations by consensus.

Exploration

SRARP survival (RNA) · tumor vs normal (RNA) · all SRARP data types